| Scoring | 1Q | 2Q | 3Q | 4Q | Final |
| Truman | 7 | 17 | 14 | 0 | 38 |
| Missouri Southern | 0 | 7 | 14 | 7 | 28 |
| Attendance: 2,000 | |||||
The Bulldogs continued their win streak against 19th-ranked Missouri Southern. Jarrett Anderson began the scoring with a 1-yard touchdown run, which was followed by a 37-yard field goal by Kyle Fischer. Anderson added another 3-yard touchdown run with 6:55 left in the second. Missouri Southern finally scratched out a score, but not before a 20-yard touchdown reception by Bret Yoder from Nate Minnis.
Anderson finished where he left off in the first half, scoring on a 14-yard run. The Lions retaliated on a 65-yard bomb, but were answered by a 12-yard scamper by Minnis to leave the game 38-14 with 4:50 left in the third quarter.
Missouri Southern made a stab late in the game with two touchdown runs, but it fell short and the Bulldogs walked away with a, 38-28, victory.
| Statistical Summary | Truman | Mo Southern |
| First Downs | 20 | 20 |
| Rushing Attempts | 54 | 45 |
| Rushing Yards | 219 | 239 |
| Passes/Attempts | 8/16 | 7/14 |
| Passing Yards | 118 | 132 |
| Punts/Average | 4/45.5 | 3/38.3 |
| Fumbles/Lost | 7/3 | 3/1 |
| Penalties/Yards | 10/66 | 3/30 |
Game Summary
Truman-Jarrett Anderson 1-yard run (Kyle Fischer PAT).
Truman-Fischer 37-yard field goal.
Truman-Anderson 3-yard run (Fischer PAT).
Truman-Bret Yoder 20-yard pass from Nate Minnis (Fischer PAT).
MSSC-Brad Cornelson 25-yard run (Lewis PAT).
Truman-Anderson 14-yard run (Fischer PAT).
MSSC-Thrash 65-yard pass from Cornelson (Lewis PAT).
Truman-Nate Minnis 12-yard run (Fischer PAT).
MSSC-Willie Anderson 24-yard run (Lewis PAT).
MSSC-Cornelson 7-yard run (Lewis PAT).
Coaches' Players of the Week
Offensive Back: Jarrett Anderson
Offensive Scout Team: John Edwards
Offensive Lineman: Jim Guntli
Receiver: Erik Nelson
Defensive Back: Tommy Hernandez
Defensive Scout Team: Ross Martin
Defensive Lineman: Matt Rose
Linebacker: Jason Rollison
Special Teams: Marion Smith
Big Hit: Zac Allison
Special Effort: Zac Allison